It's Christmastime and Rapture-time, but Stan and Francine (along with Roger) find themselves left behind while Steve and Hayley get to ascend to heaven. Stan and Francine track down Jesus and Stan strikes a deal to get himself into heaven, but at the cost of his marriage to Francine. However Stan discovers that Jesus is an imposter while Francine finds and runs off with the real Jesus. Fast forward seven years later and the war against the Anti-Christ has ravaged the world. Stan makes a deal with Jesus to rescue Francine from the Anti-Christ in return for a pass to Heaven. Now Stan, Jesus and an old friend must venture into the center of all evil to save Francine.